Bringing Together Power and Practicality
The door to true biology has been opened by the ability of the Helicos® Genetic Analysis System to directly sequence and image individual molecules. The power of the single molecule approach can only be fully realized by integrating onto a robust and versatile instrument design and combining it with easy sample preparation. Helicos recognizes this, and has coupled the power of single molecule sequencing with the practicality of a flexible, easy-to-use instrument and simple sample preparation. Detection at the single molecule level is only the beginning!
Scalability by design
Powered by Helicos tSMS™ technology, the system generates more data per run of any available sequencing technique, providing unmatched scalability. Superior data output is a result of the high density of sequenced DNA strands on the flow cell surface, as well as the 25-channel flow cell design (50 channels total). Generating this amount of data per run translates into a wealth of experimental flexibility, and into increased experimental validity.
Whether you have only tiny amounts of precious or degraded samples, or a large, genome-scale sample, the Helicos Genetic Analysis System offers:
- Breadth of coverage—Run up to 50 samples simultaneously for deep coverage across a wide area or the whole genome, including both AT-rich and CG-rich regions
- Depth of coverage—Run one sample on multiple channels simultaneously for deep coverage of a specific region
- Elimination of variation—Increase data reliability and validity by avoiding run-to-run variation, operator-to-operator variation and reagent, sample loading or hybridization variability
The scalability enabled by the technology coupled with the accuracy of single molecule sequencing means experiments with high sensitivity.
Simplicity Start to Finish:
Helicos is dedicated to enabling your success. So we combine the ability to conduct a range of different experiments on a single platform with the simplest sample preparation.
- Fewer steps saves time and money—fragment DNA, tail and hybridize to surface
- No amplification—single molecule sequencing does not require additional amplification
- Intuitive instrument operation—the instrument has an easy-to-use touch screen interface and has fully automated reagent delivery and imaging capability