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HeliSphere™ Technology Center

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Helicos recognizes the critical role collaboration plays in scientific discovery and technological advancement. To foster collaborative activity and open communication, Helicos created the HeliSphere™ Technology Center (http://open.helicosbio.com/), an open access Web site for sharing Helicos data sets and bioinformatics software tools.

 

Helicos Datasets

The HeliSphere™ Technology Center showcases datasets containing millions of single molecule sequence reads from a variety of applications performed with the Helicos™ Genetic Analysis System.

  • Caenorhabditis elegans whole genome resequencing data, highlighting the ability to obtain 27X coverage of the genome with only seven channels from a single run
  • Digital gene expression (DGE) and transcriptome sequencing (RNA-Seq) data for human brain and liver tissue samples, demonstrating sensitivity to expression levels below one transcript per million
  • Whole genome sequences of the microbes Escherichia coli, Staphylococcus aureus, and Rhodobacter sphaeroides, sequenced with consensus accuracies greater than 99.995% and showing virtually no sequence context bias

To download these datasets go to:  http://open.helicosbio.com/mwiki/index.php/Datasets

 

Open Source Project

The HeliSphere Technology Center is the gateway to Helicos’s open source project. It has the following features:

  • Offers downloadable source code and software documentation
  • Acts as a vehicle for communicating with collaborators and potential partners 
  • Supports “tarball” downloads of the source code 
  • Uses well known shared access tools, such as Wiki docs and Mailman mailing lists
  • Will contain an open bug tracking system and will entertain patch submissions from developers
  • Allows licensing of source code through the widely used free software license GPL (general public license) for general use and through a commercial license for corporate partners

Passwords to access this open source Web site are available to customers and qualified scientists upon request.

Check this site frequently! Data from a range of current Helicos projects will be posted on the HeliSphere Technology Center Web site regularly.

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