Genomics research without boundaries
The Helicos® Genetic Analysis System represents a world of research possibilities on a single sequencing platform. The most versatile genomics tool available combines a simple, universal sample preparation process and unmatched throughput to enable a virtually unlimited range of applications.
The System directly generates sequence data from any nucleic acid sample type, allowing detailed investigations of the genome and transcriptome (see examples in yellow in diagram). The System also achieves tremendous throughput, bringing within reach experiments not previously practical because of the cost and time required to process and analyze samples (see examples in grey in diagram).
Versatile technology and economic feasibility
With research possibilities limited only by your imagination, the System can help you open new research gateways and investigate the True Biology of the cell.
The System:
- Interrogates individual DNA molecules directly without the need for amplification — providing unprecedented resolution of genome biology and maximum efficiency
- Uses simple and universal amplification-free sample preparation — Any DNA or cDNA can be tailed and sequenced
- Operates at a low sequencing cost
- Achieves unmatched data output per experimental dollar — starting at over eight million usable strands per channel on each of 50 flow cell channels for a total of greater than 400 million strands per eight-day run
- Generates data on a universal platform without the need for application-specific system upgrades or extra hardware
- Has increased throughput potential equal to 10 times the current level without hardware upgrades
- Supports multiplexed samples with molecular barcodes to take full advantage of sequencing power
Current Applications:
Future applications: